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Friday 31 May 2013

Prolonged use of painkillers up the heart attack risk by 33%.


High doses of two common painkillers, Diclofenac and Ibuprofen, taken over a long period of time increases the risk of heart attack.The researchers analysed 639 random drug trials and assembled information on more than 350,000 patients, and found that for every 1000 arthritis sufferers, rate of people who suffered heart attack. These drugs have also been linked to illnesses like stomach ulcers. The study found the increased risk of cardiac side effects from ibuprofen was similar to those of another arthritis drug, Vioxx, which was withdrawn from the market almost a decade ago when research had suggested it might double the risk of heart attacks.   A new generation of NSAIDs known as coxibs were introduced, which had a lesser risk of stomach pains, but they were widely linked to an increase in heart attack, leading to public concern. 

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